In review of the several studies, although most are case reports as we do not test medication on pregnant women revealed several areas of consistency.

1) there is a possible effect of antidepressants in precipitating. spontaneous abortion and miscarriage.

2) there is no effect seen associating use of antidepressants with fetal death

3) there is a possible association between paroxetine and cardiac malformations.

4) there is a likely effect of antidepressants on preterm birth.

5) there is a probable effect of antidepressant exposure and development of a neonatal behavioral syndrome.

But, none of the effects are large and serious consequences are rare.

use of antidepressants during pregnancy, is a risk vs. ratio decision. In addition, in reviewing the studies there is no way to avoid bias for depression and the risk of depressive symptoms on pregnancy.