Fluoxetine or Prozac- both a SERT blocker and 5HT2c blocker. also a weak blocker at the NET transporter. Inhibitor of CYP 2D6 and 3A$. Because of action on the 5HT@c receptor can be activating and has anti bulimic activity.

Sertraline or Zoloft – SERT inhibition and weak DAT inhibition. Also has some affinity for the sigma 1 receptor which may have both anxiolytic as well as antipsychotic properties. weak inhibition of CYP 2D6. calming antidepressant.

Fluvoxamine or Luvox – also acts on the sigma 1 receptor to a greater degree than sertraline . Inhibitor of CYP 1A2 and 3A4. Has indication for OCD and Social anxiety disorder.

Paroxetine or Paxil – weak NET inhibitor. mild anticholinergic activity. inhibits the enzyme nitric oxide synthetase therefore problem with sexual dysfunction. Inhibitor of 2D6 and also a substrate. Withdrawal when stooping abruptly. calming. helpful with IBS because of anticholinergic activity. 

Citalopram or Celexa- mild antihistaminic property. weak inhibition at CYP 2D6. the R enantiomer is the reason for this. 

Escitalopram or Lexapro- pure SERT inhibition. more potent and less sedating than celexa.